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Server Chassis
Each Chassis comes with the Redundant Power Supply Unit Installed (RPS)
Embedded SW RAID S100i with 14 SATA ports
Embedded 4x1GbE HPE Ethernet 1Gb 4-port 369i Adapter
2-Standard Fans
HPE iLO with Intelligent Provisioning (standard)
HPE Processors
Mixing of 2 different processor models is not supported.
Processors higher than 85W will ship with the Performance heat sink. All other processors will ship with the Standard heat sink.
2 CPU models will require the selection of the Redundant Fan Cage kit (874572-B21)
Intel Xeon 1st Gen
Mixing of 2 different processor models is not supported.
Supports up to (2) processors
Intel Xeon 2nd Gen
Mixing of 2 different processor models is not supported.
Supports up to (2) processors
Tower To Rack (Optional)
Rack mode requires a redundant fan cage and redundant power supply.
Note: Only Tower Mode supports the Non-Hot-Plug PSU
Memory for Gen 1 Processors (Optional)
Supported up to (12) DIMMs per Processor
Speed of Memory will be based off the CPU Max Memory Speed.
Memory for Gen 2 Processors (Optional)
Supported up to (12) DIMMs per Processor
Speed of Memory will be based off the CPU Max Memory Speed.
Drive Options (Optional)
The 4 LFF HP or NHP chassis can be upgraded with LFF HDD cage kit (s) or LFF NHP HDD cage kit (s) to 8 or 12 LFF.
Note a field upgrade to 12 LFF either in LFF hot-plug or LFF non-hot-plug chassis will require redundant fan kit (874572-B21).
Note a field upgrade to 24 SFF will require redundant fan kit (874572-B21).
The 8 SFF NVMe Express Bay option (874569-B21) can only be installed in Box 2 on a SFF Chassis.
Maximum of 8 SFF NVMe PCIe drives are supported when two ML350 Gen10 NVMe Riser boards (shipped in 874569-B21) are populated.
Note a field upgrade to NVMe Express Bay will require redundant fan kit (874572-B21).
A Gen 10 system can support mixed SFF and LFF HDD cages in one system, for example, 4LFF + 8SFF + 4LFF based on a 4 LFF chassis.
HPE LFF Non-Hot-Plug SATA Drives (3.5in) (Optional)
Support 3 total Drive cages with a max of 12 LFF NHP SATA Drives.
Notes: HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for 10K, 15K or if all 3 Drive cages are installed.
HPE LFF Hot-Plug SATA Drives (3.5in) (Optional)
A Gen 10 system can support mixed SFF and LFF HDD cages in one system or can have LFF HP and LFF NHP mixed
Requires the HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for 10K, 15K or higher RPM
HPE LFF Hot-Plug SAS Drives (3.5in) (Optional)
A Gen 10 system can support mixed SFF and LFF HDD cages in one system or can have LFF HP and LFF NHP mixed
Requires the HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) for SAS Drives
SAS Controller or Expander is need for SAS Support.
HPE SFF Hot-Plug SATA Drives (2.5in) (Optional)
A Gen 10 system can support mixed SFF and LFF HDD cages in one system
HPE SFF Hot-Plug SAS Drives (2.5in) (Optional)
A Gen 10 system can support mixed SFF and LFF HDD cages in one system
Requires the HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) for SAS Drives
SAS Controller or Expander is need for SAS Support.
HPE NVMe Drives (2.5in) (Optional)
Must install the HPE ML350 Gen10 8 NVMe SSD Enablement Kit with 2x4NVMe Risers and Support Cables | 874569-B21 for NVMe Drive Support.
You also have the option of NVMe PCI-e Stand up cards to save a Drive Cage Slot
NVMe drives require the addition of HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21).
Max. support is one NVMe Cage
Not supported by HPE Smart Array controllers.
NVMe support is limited in SFF systems.
When running the NVMe Drives with a heavy load the fan is very loud. HPE does not recommend this for office use.
HPE M.2 Drives (Optional)
M.2 supports Software RAID only.
HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for M.2 drives.
HPE Universal SATA HHHL M.2 Kit (878783-B21) and use S100i SATA controller only.
Max. in ML350 Gen10 is one M.2 enablement card kit.
M.2 enablement card kit is limited to PCIe slot 1, 2, 3 or 4.
Cooling Fans (Optional)
Note a field upgrade to fully populate front storage bays (Box1, 2 and 3 fully loaded) will require a redundant fan kit (874572-B21)
2 CPU models will require the selection of the Redundant Fan Cage kit (874572-B21) .
Please read "Knowing your server" in the product description for all the features that require the redundant fan kit.
Processors higher than 85W will ship with the Performance heat sink. All other processors will ship with the Standard heat sink.
Networking Adapters (Optional)
(Default) Embedded 4x1GbE HPE Ethernet 1Gb 4-port 369i Adapter
The Folloing Part Numbers require the Redundant Fan Kit if installed.
- 867707-B21
- P08458-B21
- 874253-B21
- 829335-B21
Host Bus Adapters (HBAs) (Optional)
Storage Controller (Optional)
Performance RAID Controllers require the HPE Smart Storage Battery (P01367-B21) or HPE Smart Storage Hybrid Capacitor (P02381-B21) which is sold separately.
When installing an AROC you will save a PCI slot. Max 1.
GPU (Optional)
Mixing of GPUs is not supported.
The ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for ALL GPU installations.
HPE ML350 Gen10 GPU Ext Power Cable Kit (877628-B21) is required for GPU TDP larger than 75W
The 1600W RPS is recommended when the system is configured with high power GPU.
These GPUs are not recommended for use in office environment.
GPU quantity to be supported will vary based on PCI-e slots available
This server supports NVIDIA NVLink technology for specific accelerators.
PCIe x16 slots 1 and 3, use the 879289-001 power cable - PCIe slots 5 and 7, use the 876503-001 power cable
Optical Drives (Optional)
If installing a media bay Optical Drive. The HPE ML350 Gen10 Slimline ODD Bay and Support Cable Kit (874577-B21) is required.
If all three Drive cages are installed and you still need a ODD, please select the USB version.
iLO Server Management (Optional)
HPE iLO with Intelligent Provisioning (standard),
Trust Platform Module (TPM) (Optional)
HPE Trusted Platform Module 2.0 option works with Gen10 servers with UEFI Mode not Legacy Mode.
There is a FIO setting to allow this TPM module to operate in a TPM 1.2 mode (872108-B21).
Power Supply Unit (PSU)
The HPE ML350 Gen10 Flex Slot Redundant Power Supply Cage Kit with Power Distribution Board 874571-B21 comes Pre-Installed on all the chassis options.
If you select the Non-Hot-Plug PSU, the RPS will be removed.
Helpful Tip: Once desired configuration is selected click "Add to Cart". From the cart page you can submit a submit a quote request for best pricing
Chassis Options
| CTO Server [Chassis] |
HPE ML350 Gen10 4 NHP LFF CTO Server |
HPE ML350 Gen10 4 LFF CTO Server |
HPE ML350 Gen10 8 SFF CTO Server |
HPE ML350 Gen10 8 SFF Rack CTO Server |
| SKU Number |
N/A |
877625-B21 |
877626-B21 |
877627-B21 |
| Processor |
1 or 2 processors |
| DIMM Slots |
24-DIMM slots |
| Storage Controller |
Embedded SW RAID S100i with 14 SATA ports, choice of HPE modular Smart Array (AROC) and/or PCIe Standup controller card (s) |
| PCIe |
8 PCIe Gen3 slots (x16, x8, x16, x8, x16, x8, x16, x8) as standard
Notes: PCIe slots 5 – 8 require the second processor to enable.
|
| Drives Cage - included |
4 NHP LFF |
4 LFF |
8 SFF |
8 SFF |
| Network Controller |
Embedded 4x1GbE HPE Ethernet 1Gb 4-port 369i Adapter with optional 1/10/25Gb Standup card
Notes: embedded 4x1GbE HPE Ethernet 1Gb 4-port 369i Adapter does not support speeds of 100MB/s and 10MB/s.
|
| Fans |
2-Standard
Note: 2 Processors will need the redundant fan kit
|
6-Standard |
| USB |
2 front, 2 internal, 4 rear |
| Power Supply Cage included |
HPE Flex Slot RPS cage and PDB included |
| Management |
HPE iLO with Intelligent Provisioning (standard), iLO Advances and OneView (optional) |
| Tower-to-Rack conversion kit |
Optional
Notes: Please select 874578-B21 (Tower-to-Rack Conversion kit)
|
Included |
Processors | (2) Intel Xeon Scalable Gen 2
The HPE ProLiant ML350 Gen10 Tower/Rack Server supports up to 2 Intel Xeon Scalable Gen 2 processors, offering exceptional performance and scalability. Mixing processors is not supported.
1P models include 2 standard fans, while 2P models require the Redundant Fan Kit (874572-B21) to increase the total to 6 fans.
Processors with a TDP over 85W use the Performance heat sink (879150-001), while lower TDP processors use the Standard heat sink (879468-001), ensuring efficient cooling and reliable operation for demanding workloads.
Cooling | Heatsink & Fans
The Performance Heatsink (879150-001)
If the Processor you installed has a TDP of over 85W. Then the Performance Heatsink (879150-001) will replace the standard heatsink (879468-001).
The ML350 supports up to (2) CPUs. If both CPUs are installed, you will also need to install the redundant fan kit (874572-B21) which takes the system from 2 fans to a total of 6 fans.
GPUs are not recommended for use in office environments especially under stress mode when system fans are running at full speed.
The redundant fan kit (874572-B21)
The redundant fan kit (874572-B21) takes the system from 2 fans to 6 fans. Below are some configuration that require this kit.
- Both CPUs are installed
- All 3 Drive Boxes are filled
- All NVMe Drives/HHHL
- ALL GPU installations
- 10K, 15K or higher RPM SAS drives
- Required for M.2 drives
- 10 Gigabit Ethernet adapters (867707-B21)
- 25 Gigabit Ethernet adapters (P08458-B21)
- 100 Gigabit Ethernet adapters (874253-B21)
- HPE InfiniBand Cards
- ASHRAE 3 or 4 environment
- Default with RACK CTO (877627-B21)
Memory | 24 DDR4 DIMMs
Each Processor handles 12 DIMMs with a total of 24 DIMMs in a 2 Socket Configuration. The HPE ProLiant ML350 Gen10 Tower/Rack Server offers flexible memory options but does not support mixing RDIMM and LRDIMM memory types. The server supports 2933 MT/s DDR4 DIMMs with 2nd generation Intel Xeon Scalable processors, while 2666 MT/s DDR4 DIMMs are compatible with 1st generation Intel Xeon Scalable processors. This ensures optimized performance tailored to the processor generation in use, providing reliable and scalable memory support for diverse workloads.
Maximum capacity
- Max (LRDIMM) 3 TB 24 x 128 GB @ 2933 MT/s
- Max (RDIMM) 1.5 TB 24 x 64 GB @ 2933 MT/s
Storage
Mixing LFF with SFF?
HPE ML350 Gen 10 has allowed the mixing of Drive Form Factors. When doing so please select the 4 LFF CTO Server (877625-B21) as the base configuration to start with when mixing Drive Form Factors (ex. 4LFF + 8SFF + 4LFF).
4LFF None Hot-Plug (NHP) SKU supports SATA hard disk drives only. NHP drive cage is for NHP server only.
Adding NVMe Drives!
The special feature of the 8SFF Chassis (877626-B21) is the ability to add up to 8 NVMe Drives in Box 2 only. For support up to 8 NVMe drives, we need to install 2x4NVMe Risers and Support Cables (874569-B21). If only 1 Riser is installed the server can only support up to 4 NVMe drives. If you don’t want the NVMe to take up a drive bay, you can install the PCIe NVMe SSD HH/HL Enablement Cards (P26934-B - P26936-B2).
Anytime NVMe drives are installed, you'll need the Redundant Fan Cage Kit (874572-B21) installed. NVMe support is limited in SFF systems.
| Internal Storage |
Capacity |
Configuration |
| Hot Plug SFF SAS |
57.6 TB |
24 × 2.4 TB |
| Hot Plug SFF SATA |
48.0 TB |
24 × 2 TB |
| Hot Plug LFF SAS |
240.0 TB |
12 × 20 TB |
| Hot Plug LFF SATA |
240.0 TB |
12 × 20 TB |
| Hot Plug SFF SAS SSD |
368.64 TB |
24 × 15.36 TB |
| Hot Plug SFF SATA SSD |
92.16 TB |
24 × 3.84 TB |
| Hot Plug LFF SAS SSD |
92.16 TB |
12 × 7.68 TB |
| Hot Plug LFF SATA SSD |
92.16 TB |
12 × 7.68 TB |
| Non Hot Plug LFF SATA |
48.0 TB |
12 × 4 TB |
| Hot Plug SFF NVMe PCIe SSD |
61.44 TB NVMe |
8 × 7.68 TB NVMe |
Expansion Slots
Since there are only 8 PCI-e Slots, a Double-Wide GPU takes up two slots. We can quickly run out of room if we are not carefully thinking of the entire configuration. If you have 8 NVMe Drives installed. That means you have 2 PCI-e slots being used up and they have dedicated slots of 1 and 3. While if you have 24 SFF drives installed that means you have the SAS Expander card in the dedicated PCI-e slot 4 and up to 2 Smart Array in support. In each configuration, the GPU quantity will vary.
| Slots # |
Technology |
Bus Width |
Connector Width |
Slot Form Factor |
Notes |
| 1 |
PCIe 3.0 |
X16 |
X16 |
Full-height, full-length slot |
Proc 1 |
| 2 |
PCIe 3.0 |
X4 |
X8 |
Full-height, full-length slot |
Proc 1 |
| 3 |
PCIe 3.0 |
X16 |
X16 |
Full-height, full-length slot |
Proc 1 |
| 4 |
PCIe 3.0 |
X4 |
X8 |
Full-height, full-length slot |
Proc 1 |
| 5 |
PCIe 3.0 |
X16 |
X16 |
Full-height, full-length slot |
Proc 2 |
| 6 |
PCIe 3.0 |
X8 |
X8 |
Full-height, full-length slot |
Proc 2 |
| 7 |
PCIe 3.0 |
X8 |
X8 |
Full-height, full-length slot |
Proc 2 |
| 8 |
PCIe 3.0 |
X8 |
X8 |
Full-height, full-length slot |
Proc 2 |
GPU Accelerators
GPU Requirements
- All GPUs require the Redundant Fan Cage Kit (874572-B21).
- Mixing of GPUs is not supported.
- HPE ML350 Gen10 GPU External Power Cable Kit (877628-B21) is required with GPU modules TDP larger than 75W
The 1600W RPS (830272-B21) is recommended when configuring the system with a high-powered GPU. The 800W RPS will work too (per GPU).
Notes:
These GPUs are not recommended for use in office environments especially under stress mode when system fans are running at full speed.
NVLINK Supported
This server supports NVIDIA NVLink technology for specific accelerators. This technology allows two matching accelerators to communicate directly through a high-speed interconnection— NVLink bridge. This interconnection effectively combines the available memory of both accelerators for increased workload performance.
2nd Gen Intel Xeon Supported GPUs
The following GPUs only work with 2nd Gen Intel Xeon Processors.
- NVIDIA T4 16GB Computational Accelerator for HPE (R0W29C)
- NVIDIA A2 16GB PCIe Non-CEC Accelerator for HPE (R9H23C)
Storage Controllers
The HPE ML350 Gen10 come installed with the Embedded SW RAID S100i onboard SATA Storage Controller. This S100i can support up to 14 SATA drives. When using this S100i the cable kits are different. S100i LFF Cables (877578-B21), S100i SFF Cabled (877579-B21).
This S100i can be upgraded with an AROC Module or a PCIe Adapter Card. The AROC has a dedicated connector and does not take up a PCIe slot.
Flash Back Write Cache (FBWC)
Hewlett Packard Enterprise offers two centralized backup power source options to back up write cache content on P-class Smart Array controllers in case of an unplanned server power outage. One energy pack option can support multiple devices. An energy pack option is required for P-class Smart Array controllers. The HPE Smart Storage Hybrid Capacitor is only supported on Gen10 and later servers.
Let’s talk power!
All three models come with the Redundant Power Supply (RPS) (874571-B21) and a PDB. This RPS can hold up to 2 PSU depending on the desired power needed. The mixing of 2 different power supplies is NOT allowed. The selection of two HPE Flex Slot power supplies provides 1+1 power redundancy. The 1600W RPS is recommended when the system is configured with a high-power GPU. The 800W RPS will work too (per GPU) – depending on the configuration. With GPUs you will need this cable kit as well (877628-B21).
If you want to revert to the Non-Hot-Plug PSU, the RPS will be removed and you must select the tower version.
Lights Out! iLO 5
iLO 5
A remote server management processor embedded on the system boards of HPE ProLiant servers and Synergy compute modules. iLO enables the monitoring and controlling of servers from remote locations.
iLO RESTful API
Redfish API conformance and offers simplified server management automation such as configuration and maintenance tasks based on modern industry standards.
HPE OneView Standard
can be used for inventory, health monitoring, alerting, and reporting without additional fees. It can monitor multiple HPE server generations. The user interface is like the HPE OneView Advanced version, but the software-defined functionality is not available.
Dimensions & Weight
Dimensions
Tower
- 46.25 (H) x 64.8 (D) x 17.4 (W) cm
- 18.2 (H) x 25.51 (D) x 6.85 (W) in
Rack – System only
- 17.4 (H/4U) x 64.8 (D) x 44.5 (W) cm
- 6.85 (H) x 25.51 (D) x 17.52 (W) in
Tower-to-Rack Conversion Kit (1U)
- 4.445 (H/1U) x 69.2 (D/without CMA. Depth with CMA: 83.5) x 45.2 (W) cm
- 1.75 (H/1U) x 27.23 (D/without CMA. Depth with CMA: 32.89) x 17.795 (W) in
Smart Array type-a (AROC) Module
Smart Array type-p or HBA card
